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Acid: is an
antioxidant which boosts the levels of glutathione. It is an essential
factor taking part in reactions involving the production of energy in the
cell. It is used to generate energy in the mitochondria. It helps in
eliminating toxic metals and protects against the process of
Ascorbate (Vitamin C in
the form of Niacinamide Ascorbate), is reversibly oxidized to
dehydroascorbic acid, thus forming full biologic activity. Ascorbic acid
is a reducing agent involved in numerous oxidation-reduction reactions and
transfer of protons (as in the production of energy). It is essential in
the synthesis of collagen, catecholamines, corticosterone, the metabolism
of tyrosine, improves nonheme iron absorption, stabilizes cell membranes,
helps to maintain the integrity of connective tissue, osteoid tissue of
bone, and dentin of teeth. It is an aldose reductase inhibitor,
antihistamine effect, delays the insulin response to glucose challenge,
exerts vasodilatory, and anti clotting affects by altering the production
Biotin: is a coenzyme vitamin that is
essential in carbohydrate and fatty acid metabolism by increasing levels
of carboxylase enzymes which catalyze essential
metabolic reactions. Specifically, biotin is involved in the utilization
of glucose, the breakdown and utilization of fatty acids in energy
metabolism. It is also a component of cell growth and replication. It
enhances sensitivity to insulin, and therefore, reduces lipogenesis (fat
creation). It is also involved in the transformation of amino acids into
protein. Biotin aids in digestion and the breakdown of fats. Biotin is a
cofactor in the utilization of protein, folic acid, pantothenic acid, and
L- Carnitine is a trimethylated amino acid which is absolutely essential for the transformation
of fatty acids into energy for muscular activity. Supplementation can improve
fat metabolism aiding in weight loss. In
addition, studies suggest supplementation can improve exercise capacities and
endurance, possibly through its vasodilatation property, which both improves
energetic metabolism of the muscle and enhances wash-out of algogenic
metabolites. L-carnitine supplementation has also shown evidence in preventing
cardiovascular disease, reducing serum cholesterol and triglycerides, and
improving heart function.
Choline is a lipotropic
substance, which functions in the body's metabolism as an agent that aids in
the digestion and emulsification of fats. It is believed that choline helps the body to
burn fat, and thereby acts as an agent supporting weight loss. As
choline increases fat metabolism it has shown that it lowers blood
cholesterol. Fats and oils are an essential part of the
diet, yet they must function within the watery environment of the body. When
choline is converted to phosphatidylcholine it helps to dissolve fats and cholesterol,
and therefore functions as the body's emulsifier.
Chromium Nutritional Yeast, a single cell fungi that is fed
nutrients including chromium. The yeast then assimilates the nutrients into
highly bio-available forms including Glucose Tolerance Factor (GTF), a
compound of chromium, nicotinic acid, and amino acids. GTF potentiates
insulin's action and therefore influences carbohydrate, lipid and protein
metabolism, reducing body fat and increasing lean muscle mass, plus decreases
serum cholesterol and triglycerides. Chromium
is highest in infancy and decreases steadily with age.
Unless it is in a biological form, it cannot be used in the body.
It is estimated that as many as 90% of American diets are low in
chromium. Chromium can be difficult for the body to absorb, however, this form
(GTF) is already biologically assimilated and ready for direct absorption into your
cells. Our nutritional yeast also
contains high levels of other important nutrients, including all the B
vitamins (except for B-12 which we have added separately), 16 amino acids and
14 minerals. The B-complex
vitamins support and optimize carbohydrate, fat, and protein metabolism.
They also reduce stress, depression, irritability and fatigue and also
help protect against aging. The
body does not store B vitamins, so they continually need to be replenished.
Biotin, one of these B vitamins, enhances insulin sensitivity, and
therefore helps with fat metabolism as well.
aurantium: herbal extract; directly stimulates beta-3 receptors
on the surface of fat and muscle cells, which cause an increase in the rate of
lipolysis or breakdown of fat which then causes an increase in thermogenesis
or metabolic rate, which burns calories. This increase in fat metabolism
increases the body's available energy. This is important in exercise to
minimize loss of lean muscle tissue and enhance physical performance.
forskolii: Herbal Extract, has demonstrated the ability
to promote lean body mass while reducing body fat and reducing weight Directly activates adenylate
cyclase, which leads to the activation of lipase enzyme, which breaks down the
triglyceride foundation of fat. Additionally,
it has been shown to stimulate the thyroid whose hormonal signals are central to metabolism.
The biochemical mechanism of maintaining or increasing lean body mass is related to the availability of cyclic
AMP. By facilitating hormonal action, cyclic AMP may regulate the body's thermogenic response to food, increase the body's
basil metabolic rate (BMR), and increase utilization of body fat (since thermogenesis is preferentially fueled by fatty acids derived from body fat and/or food).
These events also correspond to the buildup of lean body mass.
Linoleic Acid (CLA): is a
form of linoleic acid in which the double-bonds are closer together. CLA
works to normalize glucose tolerance and reduce the production of insulin
(insulin inhibits lipolysis).
CLA has been shown to reduce body fat, improve
muscle tone, improve nutrient usage, and reduce the appetite by improving the
way the body extracts energy from less food. CLA is able to block the
converstion of Dihomogamma Linolenic Acid (DGLA) into arachidonic acid
(AA). DGLA which is not converted, can instead be used to make the
"good" prostaglandin PGE1 (as opposed to "bad"
prostaglandin PGE2 which is made from AA). PGE1 stimulates the
production of cAMP which leads to accelerated lipolysis (fat breakdown).
By maintaining adequate cellular levels of PGE1 you are guaranteed that a
certain baseline level of cyclic AMP is always present in a cell. When an
additional burst of cyclic AMP is generated by an endocrine hormone (such
as glucagon), the overall cyclic AMP levels in the cell will be high
enough to ensure that the appropriate biological response (i.e. lipolysis,
thermogenesis, release of growth hormone, etc.) is produced.
( B-12) is required by the enzyme that
facilitates the conversion of L-methylmalonyl-CoA to succinyl-CoA. This
biochemical reaction plays an important role in the production of energy from
fats and proteins. B-12 is essential for
the formation of choline-containing phospholipids that emulsify fats in the
body's water environment. B-12 is also
required for the function of the enzyme, methionine synthase. Inadequate
function of methionine synthase can lead to an accumulation of homocysteine,
which is a primary indicator of the cardiovascular disease process. B-12 is
also important in red blood cell production and preventing erythropoiesis (low
red blood cell anemia) which is common with hypothyroidism (as many as 30-40%
Essential Oil: stimulates
the thyroid to burn fats. This effect, coupled with its diuretic and
expectorant properties, explain fennel's reputation for cleansing the body,
including the liver and spleen, of toxins and poisons, and its use for weight
loss and reduction of
Folic Acid: is
converted to methyl tetrahydrofolate (Me-THF), and as such, provides labile
methyl groups used to recycle homocysteine to methionine. With an
insufficiency of Me-THF, more homocysteine is converted to cystathionine
instead of being recycled into methionine. This undercuts methylation
metabolism and the reproduction of methionine. Methionine is required for
the production of S-adenosylmethionine (SAM), the "active methyl
donor" that is a vital part of countless metabolic reactions throughout
the body. An under-activity of the folate cycle coupled with overproduction
and diversion to the cystathionine pathway diverts the homocysteine from the
SAM cycle. Also homocysteine in all but low quantities can damage the
endothelial cells of arteries. Folic acid supplementation improves arterial
endothelial function and has potential implications for prevention of
atherosclerosis in people with hyperhomocysteinemia. Folic acid is also important in red blood
cell production and preventing erythropoiesis (low red blood cell anemia)
which is common with hypothyroidism (as many as 30-40% of patients).
Cambogia: herbal extract; contains HCA (hydroxycitric acid), which
inhibits the conversion of glucose into fat by the enzyme citrate lyase,
thereby effectively preventing the creation of fat (lipogenesis). HCA also
boosts basal metabolic rate, which is usually suppressed during a reduced
calorie diet. This keeps weight-loss from slowing down when you restrict
extract of the exudate (gum guggul) of Mukul myrrh tree (Commiphora mukul), contains
phytosterols named guggulsterones, organic acids, aromatic acids, diterpenes,
lignans, and fatty acid alcohols. Its effect is to lower lipid levels in the bloodstream
and stimulate the thyroid gland. Specifically, gugulipid lowers VLDL and LDL cholesterol
and triglycerides while simultaneously raising HDL cholesterol. This indicates Gugulipid's
primary use for providing a protective effective against atherosclerosis. These effects
are due to gugulipid's action on the liver and thyroid. The thyroid is stimulated to
increase the body's metabolic rate, and the liver is stimulated to metabolize LDL
cholesterol, effectively lowering the amount in the bloodstream.
Gugulippid's effect on serum cholesterol and triglycerides,
is comparable to that of other lipid-lowering drugs, but without significant side effects
In addition to protecting against the formation of
atherosclerotic plaques, gugulipid provides regression of preexisting plaques, plus mildly
inhibits platelet aggregation and promotes fibrinolysis, which are factors involved
in stroke and embolic events.
Iodine: Iodine is needed to
make thyroid hormones, which are necessary for maintaining normal metabolism
in all cells of the body.
Thyroid hormone synthesis is: dependent on Iodine and L-tyrosin (see
Iodine is an essential component of the thyroid (metabolic) hormones T3
and T4. Most of ingested iodine is absorbed by active transport into
the blood from the gastrointestinal tract and converted to iodide (ionized
form) in the process. Iodide is then actively transported into the thyroid
cells and incorporated into thyroglobulin (~1% metabolized per day).
Iodide is converted back to iodine and used with tyrosine for hormone
Thyroid Hormone's Effects
- METABOLIC RATE: Increased BMR (Basil Metabolic Rate)
- CALOROGENIC: Increased heat production (oxidative metabolism)
- SYMPATHOMIMETIC: Flight or Fight response
- CARDIOVASCULAR: Increases responsiveness of heart.
- GROWTH: Essential for normal growth
- (PERMISSIVE OR SYNERGYSTIC WITH Growth Hormone, Insulin-Like Growth
Factor, CNS, ANS
- NERVOUS SYSTEM: Development and adult activity.
digitata (kelp): Kelp is an excellent source of B vitamins,
calcium, magnesium and iodine. Iodine is essential for the formation of the
thyroid hormones. One of the key symptoms of Iodine Deficiency is fatigue.
It's certainly not the only one, but it may be a key indicator that your
thyroid gland is not functioning properly. And that can have very significant
impacts on your health. Some of the other symptoms of under active thyroid is
weakness, lethargy, weight problem, edema, and shortness of breath. The
thyroid gland is considered to be the 'thermostat' of the body, controlling
the metabolism (rate at which food or nutrients are utilized) of the entire
system. If it is not working properly the entire system is affected. About 1
out of 6 people in the world are at risk of iodine deficiency.
(vitamin B-3) has been used for many years to treat hyperlipidemia. It has
been shown to reduce coronary death and non-fatal myocardial infarction. It
reduces total cholesterol, low density lipoprotein cholesterol (LDL-C) and
triglycerides and increases high density lipoprotein cholesterol (HDL-C).
Niacin also favorably influences other lipid parameters. The active form of
this coenzyme, nicotinamide adenine dinucleotide (NAD), is essential for
glycolysis (the enzymatic breakdown of carbohydrates.)
Riboflavin (Vitamin B2) is a
water-soluble vitamin, that consists of a heterocyclic isoalloxazine ring
attached to a sugar alcohol side chain, ribitol. Riboflavin is phosphorylated
into the coenzyme flavin mononucleotide (FMN) and ultimately converted to
flavin adenine dinucleotide (FAD). FMN and FAD participate in
oxidation-reduction reactions and in energy production via the respiratory
chain through electron transfer. Riboflavin is crucial for the metabolism
of carbohydrates, amino acids, and lipids.
Selenomethonine: ( Selenium) In animal studies, selenium deficiency
causes a markedly reduced serum level of glutathione peroxidase (Glutathione
is a tripeptide and when combined with vitamin E and selenium, forms
glutathione peroxidase which is one of the key antioxidants that protects
the body and is critical for protection of the thyroid gland from oxidation
damage. Low levels of glutathione (along with low levels of vitamin E and
selenium) may be a factor in the genesis of thyroid disease. Excessive
intake of sugars and starches may reduce glutathione and thereby damage the
thyroid gland.) Selenium-deficient animals had lower concentrations of the
thyroid hormones T3 and T4 than selenium-adequate animals. In the elderly,
reduced peripheral conversion of T4 to T3 with a lower T3/T4 ratio and overt
hypothyroidism are frequently observed. Iodothyronine 5' deiodinase, which
is mainly responsible for peripheral T3 production (the more active form),
has recently been demonstrated to be a selenium containing enzyme. The
activity of hepatic type I 5'deiodinase was decreased by 47% by selenium
deficiency compared to controls, demonstrating that selenium also plays an
important role in thyroid hormone metabolism.
is an amino
acid precursor for synthesis of the bodies neurotransmitters and thyroid
hormones. Tyrosine acts in the thyroid gland to support metabolic function, reduce body
fat and suppress ones appetite. Low levels can lead to depression, low blood
pressure and temperature, and hypothyroidism.
Zinc acetate: Zinc helps normalize blood
sugar. This is important, because high blood sugar stimulates over
production of insulin, which besides inhibiting lipolysis (fat breakdown),
also reduces a hormone called leptin, which regulates appetite and causes
satiety (turns off hunger). Zinc supplementation tends to keep leptin from
being suppressed even when sugar is consumed. Zinc is stored primarily in
muscle but high concentrations are also found in red and white blood cells
and the retina. In men, the prostate gland contains more zinc than any other
organ. Dietary zinc restriction in normal young men has demonstrated a
significant decrease in serum testosterone concentrations, therefore zinc
may play an important role in modulating serum testosterone levels. Zinc is a part of some important antioxidant compounds, including
superoxide dismutase (SOD) and zinc monomethionine. It protects the liver
from chemical damage, helping with detoxification of the body. It is
required for a healthy immune system and is essential for proper growth and
development including muscle growth. In animal studies, Zinc deficiency
decreased concentrations of the thyroid hormones triiodothyronine (T3) and
free thyroxine (fT4) in serum by approximately 30% and the activity of
hepatic type I 5'deiodinase was decreased by 67%, demonstrating that zinc
plays an important role in thyroid hormone metabolism. The structure of
nuclear thyroid hormone receptors contains Zinc ions which are crucial for
the functional properties of the protein.
Please note: This information is not intended to diagnose,
or prescribe any form of treatment. The statements in this information have not been
evaluated by the Food and Drug Administration. The products herein are not intended to
treat, cure, or prevent any disease, and are meant solely for Health Education purposes
alone. If you are suffering from any illness or medical complaint, always first seek the
advice of your physician.